[KB2390] Are ESET products compatible with Windows Defender?
Microsoft Windows Defender is a program that comes enabled by default with Windows Vista, Windows 7, Windows 8, and some version of Windows 10.
You are not required to remove ESET on Windows 10
Depending on your version of Windows 10, you may receive a notification from Windows suggesting that you disable ESET. You are not required to disable ESET to use Windows 10. See our Knowledgebase article for details about Windows Defender behavior.
Windows Vista/7: All ESET products are completely compatible with Microsoft Windows Defender. Windows Defender does not contain any antivirus functionality, so you will not need to uninstall or disable Microsoft Windows Defender when installing your ESET product.
Disable Windows Defender in Windows 10 manually
Disable Windows Defender only if your ESET product is installed on your system or if advised by ESET Technical Support.
Click the Windows icon → Settings.
Click Update & security.
Click Windows Security in the left sidebar and select Virus & threat protection.
Scroll down to Windows Defender Antivirus options and open it. Disable Periodic scanning.